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Conditions

TOFI — normal-weight obesity

"Thin outside, fat inside"

TOFI — normal weight on the outside, visceral fat inside

TOFI (thin outside, fat inside) is a state where weight and BMI are normal, but the share of fat, especially visceral fat, is elevated. Such people are described as "metabolically obese at a normal weight".

Outwardly the person is slim, but metabolically they are closer to people with obesity.

Why a normal weight is misleading

BMI accounts only for weight and height and does not distinguish fat from muscle. You can have a normal BMI but excess visceral fat, fat in the liver (steatosis) and little muscle. It is estimated that up to ~29% of people with a normal BMI have a body-fat share in the "obese" range.

Why it is dangerous

Visceral fat raises insulin resistance, sustains chronic inflammation and increases the risk of type 2 diabetes and cardiovascular disease — almost as much as overt obesity.

How to detect it

BMI is not enough. Look at body-fat percentage, waist circumference and the waist-to-height ratio, and body composition (bioimpedance, DEXA). A large waist and poor lab results at a "normal" weight should raise a flag.

Calculate using this marker

Calculators where TOFI (normal-weight obesity) is used directly:

Frequently asked questions

Can you be thin but obese?

Yes — that is exactly TOFI. At a normal weight you can have excess visceral fat, insulin resistance and poor lab results. Outward slimness does not guarantee metabolic health.

How do I know if I have TOFI?

Assess more than just weight: measure your waist and waist-to-height ratio, check body-fat percentage and body composition, and test glucose, HbA1c and lipids. A large waist and poor labs at a normal BMI are a reason to suspect TOFI.

Related terms

Sources

  1. Thomas EL et al. / TOFI phenotype and its effect on the occurrence of diabetes. PubMed, 2017
  2. TOFI (thin outside, fat inside) — overview
info
This content is educational and does not replace consultation with a physician. Reference ranges may vary depending on the laboratory and method — rely on the ranges stated on your own test report.
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